The New York Giants and the Dallas Cowboys kick off the NFL’s Week 4 slate of games with a Thursday night matchup at the Meadowlands. The 1-2 Cowboys enter the game as favorites over the 1-2 Giants, who are fresh off their first win of the season. This is the final full week of action before teams start going on bye in Week 5, which means 13 games on Sunday along with another Monday Night Football doubleheader, this time featuring the Tennessee Titans and Miami Dolphins (7:30 p.m. ET on ESPN) and the Seattle Seahawks and Detroit Lions (8:15 p.m. ET on ABC and ESPN+).
Here’s a look at all the Week 4 games. Football Power Index (FPI) by ESPN Sports Analytics. Odds current as of publication time. For most current odds go to ESPN BET
MORE NFL BETTING CONTENT: My First Bet: Early picks for NFL Week 4 | Solak’s Week 4 picks (E+) | Walder’s props (E+)
Cincinnati Bengals -4.5 vs. Carolina Panthers
Sunday, 1 p.m. ET, FOX
Line movement: Opened Bengals -5.5
“Money Line: Bengals (-215) ; Panthers (+180)
Total: 46.5; Opened: 44.5
FPI favorite: Bengals by 6, 64.3% to win outright
Philadelphia Eagles -2 vs. Tampa Bay Buccaneers
Sunday, 1 p.m. ET, FOX
Line movement: Opened Eagles -2.5
“Money Line: Eagles (-125) ; Buccaneers (+105)
Total: 43.5; Opened: 46.5
FPI favorite: Eagles by 4.2, 62.1% to win outright
Denver Broncos vs. New York Jets -7.5
Sunday, 1 p.m. ET, CBS
Money Line: Broncos (+290) ; Jets (-360)
Total: 39.5; Opened: 38.5
FPI favorite: Jets by 8.5, 70.8% to win outright
Minnesota Vikings vs. Green Bay Packers -3
Sunday, 1 p.m. ET, CBS
Money Line: Vikings (+125) ; Packers (-145)
Total: 43.5; Opened: 42.5
FPI favorite: Packers by 1.5, 53.9% to win outright
Los Angeles Rams vs. Chicago Bears -3
Sunday, 1 p.m. ET, FOX
Money Line: Rams (+135) ; Bears (-155)
Total: 40.5; Opened: 40.5
FPI favorite: Rams by 0.2, 51.5% to win outright
New Orleans Saints vs. Atlanta Falcons -2.5
Sunday, 1 p.m. ET, FOX
Money Line: Saints (+115) ; Falcons (-135)
Total: 42.5; Opened: 43.5
FPI favorite: Saints by 0.4, 51.5% to win outright
Pittsburgh Steelers -1.5 vs. Indianapolis Colts
Sunday, 1 p.m. ET, CBS
Line movement: Opened Steelers -1.5
“Money Line: Steelers (-125) ; Colts (+105)
Total: 40.5; Opened: 39.5
FPI favorite: Steelers by 1.3, 53.5% to win outright
Jacksonville Jaguars vs. Houston Texans -6
Sunday, 1 p.m. ET, CBS
Money Line: Jaguars (+220) ; Texans (-270)
Total: 45.5; Opened: 45.5
FPI favorite: Texans by 4.4, 61% to win outright
New England Patriots vs. San Francisco 49ers -10.5
Sunday, 4:05 p.m. ET, FOX
Money Line: Patriots (+475) ; 49ers (-650)
Total: 40.5; Opened: 40.5
FPI favorite: 49ers by 11.8, 77.7% to win outright
Washington Commanders vs. Arizona Cardinals -3.5
Sunday, 4:05 p.m. ET, FOX
Line movement: Opened Cardinals -5.5
“Money Line: Commanders (+155) ; Cardinals (-185)
Total: 50.5; Opened: 49.5
FPI favorite: Cardinals by 4.1, 60.4% to win outright
Cleveland Browns vs. Las Vegas Raiders -2
Sunday, 4:25 p.m. ET, CBS
Line movement: Opened Browns -0.5
“Money Line: Browns (+105) ; Raiders (-125)
Total: 37.5; Opened: 37.5
FPI favorite: Browns by 0.3, 53% to win outright
Kansas City Chiefs -7 vs. Los Angeles Chargers
Sunday, 4:25 p.m. ET, CBS
Line movement: Opened Chiefs -7
“Money Line: Chiefs (-380) ; Chargers (+300)
Total: 39.5; Opened: 39.5
FPI favorite: Chiefs by 5.3, 63.2% to win outright
Buffalo Bills vs. Baltimore Ravens -2.5
Sunday, 8:20 p.m. ET, NBC, Peacock
Money Line: Bills (+115) ; Ravens (-135)
Total: 46.5; Opened: 45.5
FPI favorite: Bills by 2.1, 55.7% to win outright
Tennessee Titans vs. Miami Dolphins -1
Monday, 7:30 p.m. ET, ESPN
Money Line: Titans (+100) ; Dolphins (-120)
Total: 36.5; Opened: 36.5
FPI favorite: Titans by 2.4, 57% to win outright
Seattle Seahawks vs. Detroit Lions -3.5
Monday, 8:15 p.m. ET, ABC, ESPN+
Money Line: Seahawks (+165) ; Lions (-195)
Total: 45.5; Opened: 48.5
FPI favorite: Lions by 4.7, 62.1% to win outright